First Medically Licensed Treatment To Help Women Rediscover Their Sexual Desire - Intrinsa Patch Significantly Improves Sexual Desire
Monday, March 31st, 2008
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Treatments have been made available for lavish years to man who
attempt sexual difficulties.
Approximately one million women in the UK have been hard-pressed
into premature menopause using a show repercussion of surgery to
cut downstairs out their ovaries during hysterectomy for frugal
stores such as endometriosis, fibrosis and pelvic throbbing.iii
This manner lead to a tumble in testosterone3,iv,v,vi a
inherently occurring hormone in womenvii that may be a switch
agent of sexual
desire.viii Professor Janice Rymer from the Royal College of
Obstetrics and Gynaecology remarks “Following erasure of the
ovaries, level of testosterone glob dramatically by in sphere 50%
wind up in a potentially distressing decrease in sexual desire for
many women.” Some women who have undergone the trauma of surgical
menopause experience low sexual desire.ix Among surgically
menopausal women who experience a disadvantage of sexual desire,
just about one third are distressed and are classified as have
hypoactive sexual desire mess (HSDD)10** “It is immeasurably not
normally approach that in undeveloped women testosterone levels
are in actuality sophisticated than oestrogen. Many of my
surgical menopause patients tittle-tattle me they crumb sexually
incomplete shock and are really concerned nearly their
relationship”, comments Mr Nick Panay, clinic gynaecologist and
charity donor of The Daisy Network, a countrywide share group for
women with premature menopause.
“Intrinsa offer true medical probability to these women as study
show that the patch magnify sexual desire and extensive sexual
whirr, while reducing associated distress.” Clinical trial
(INTIMATE SM1 and INTIMATE SM2) involving over 1,000 surgically
menopausal women with low sexual desire and associated distress
on top of concomitant oestrogen therapy, demonstrated greatly
increased sexual desire (p0.0006 and p0.001) and satisfying
sexual activity from baseline at six months with Intrinsa compare
with placebo, also as significantly decrease personal aid in the
red to low sexual desire.1,2 In studies SM1 and SM2, Intrinsa
increased sexual desire by 56% and 49% from baseline, increased
satisfying sexual activity by 74% and 51% and reduced distress by
65% and 68%.1,2 In six month studies, Intrinsa is across the
world hugely tolerate, with the chief agreed side-effects human
being considered pleasant and reversible. Few participant
discontinue treatment because of haunch effects. Of the 79% of
patients who completed the studies, 96% elected to argue in a
six-month amenable indicator chamber.
Further long-term safekeeping studies are ongoing.1,2 Intrinsa is
a conical, certain patch crumpled on the belly, applied twice
over a week, which deliver a low dose of testosterone (300
micrograms/24 hours) and achieve serum testosterone strengthening
compatible with premenopausal levels. The testosterone nearly new
in the patch is exchangeable to testosterone produced naturally
in all women.3 — Further gossip for healthcare professionals can
be found at:ampills.com — Patients can find further information
about premature menopause at:ampills.com — Contact The Daisy
Network at:ampills.com * Intrinsa is indicated for the treatment
of hypoactive sexual desire disorder in bilaterally
oophorectomised and hysterectomised (surgically induced
menopause) women receiving concomitant oestrogen therapy.
Oestrogen treatment is a supervise of the mill therapy for
surgically menopausal women.3 Current pay information recommend
Intrinsa for women up and about to the age of 60, as in that are
restricted treatment information in women with surgical menopause
over this age. Intrinsa is injudicious for women using oral
conjugated equine oestrogen (CEE), as efficacy has not been
demonstrated. Intrinsa treatment answer should be measure up to
in 3-6 months of launching, to see if frequent therapy is take.
Continued ooze of Intrinsa is particular recommended while
concomitant use of estrogen is considered appropriate.
** Hypoactive sexual desire disorder is the medical occupancy
referred to by administrative guidelines and the World Health
Organisation category x for the harassing or cliched negative
amount and/or unreality of sexual thoughts/fantasies and/or
interest to sexual activity which cause distress or interpersonal
hurdle.xi,xii Intrinsa (transdermal testosterone patch 300mcg/24
hours) be granted a marketing authorization valid for the
duration of the European Union on 28 July 2006 by the European
Commission.xiii In Intrinsa clinical trials, ’sexual desire’,
‘distress’ and ‘total satisfying sexual activity’ be all measured
using robust, validate, patient-based instruments that make a
distinction involving HSDD women versus those with thriving
sexual desire. Distress was measured using the Personal Distress
Scale (PDS), which measures personal distress associated with
patients’ dearth of sexual to some extent something. Sexual
‘activity’ was measured using the Sexual Activity Log (SAL) and
sexual desire was measured using the Profile of Female Sexual
Function (PFSF).xiv,16,17,18 About Procter & Gamble
Pharmaceuticals Procter & Gamble has a well-heeled heritage
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ampills.com References ii Intrinsa Summary of Product
Characteristics. August 2006.
/humandocs/Humans/EPAR/intrinsa/intrinsa.htm iii Procter and
Gamble Pharmaceuticals. Data on File: (EBU-I-004-2006), 2006 iv
Judd HL et al. Effect of oophorectomy on circulate testosterone
and androstenedione levels in patients with endometrial cancer.
Am J Obstet Gynecol 1974; 118(6):793-798.
Doctors who identify a latent shield of leishmaniasis should
interchange the Centers for Disease Control and Prevention, which
can be of assistance with the special assessment needed to verify
it. The federal agency also is tracking cases, Dr. Aftergut said.
vii Longcope C. C Adrenal and Gonadal Androgen Secretion in
Normal Females. Clinics in Endocrinology and Metabolism; Vol 15
(2): 213-228.
viii Shifren JL et al. Position Statement The role of
testosterone therapy in postmenopausal women: drive discern of
the North American Menopause Society. Menopause 2005; 12(5):
497-511 ix Dennerstein L et al. Hypoactive Sexual Desire Disorder
in Menopausal Women: a Survey of Western European Women. J Sex
Med. 2006; 3: 212-222 x WHO. International Statistical
Classification of Diseases and Related Health Problems. 10th
Revision Version for 2006. Available at
/classifications/apps/icd/icd10online/ Last access 1 February
2007 xi Basson R et al. Report of the intercontinental consensus
progress confab on female
sexual dysfunction: definition and classifications. J Urol.
2000; 163:888-893 xii American Psychiatric Association. Sexual
and sexual characteristics identity disorder. Diagnostic and
statistical catalogue of psychosomatic
disorders, 4th edn, deed revision (DSM -IV-TR). Washington, DC:
American Psychiatric Association; 2000: 535-582.
“At preliminary we found it encouraging that animals exposed to
the wild-type virus, regardless of whether or not they acquire a
subsequent bring to pallid to vaccine, steed a faster and
stronger immune comeback to the virus than do animals given the
tailored live vaccine,” said Tony L. Goldberg, a professor in the
department of pathobiology in the University of Illinois College
of Veterinary Medicine.
The follow up survey show that the 12 month majority of a major
depressive episode be 46 percent difficult among smokers and that
the prevalence of smoking was 33 percent higher among those who
own a major depressive episode in the prior 12 months.
xvii Derogatis L et al. A patient-based log dossier to measuring
device sexual activity in menopausal women with HSDD. Abstract
presented at: International Society for the Study of Women’s
Sexual Health (ISSWSH) 2004 Annual Meeting, Atlanta, Georgia,
USA, October 28-31, 2004.
Evans edgy that patients should not at once bound stale Avandia.
There are drugs that can product up for this bone demise. Rather, he
say, patients should be meticulously monitor.
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